Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
May 07, 2018 - May 08, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
other: A.24. Partition coefficient n-octanol/water
Version / remarks:
European Commission Regulation (EC) No. 440/2008 and No. 2016/266
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
3.2
Temp.:
25 °C
Remarks on result:
other: pH: Not relevant

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test item was determined to be 3.2.
Executive summary:

The partition coefficient n-octanol/water of the test item was determined according to the HPLC method (OECD 117, EU Method A.24). The shake flask method was not applicable as it was not possible to obtain a clear solution of the test item in n-octanol in appropriate concentrations. It was found to be: 3.2.