Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 223-517-5
CAS number: 3937-56-2
Doses, mortality/ animals treated
animal died due to intubation error, excluded from mortality assessment
Main study group body weights
Body weights (mg/kg bw)
In a rat
acute oral toxicity study 5 male and 5 female Sprague-Dawley rats
received as single oral dose (via gavage) of 1,9-Nonanediol suspended in
0.5% w/v methylcellulose at 1260, 2000, 3200, 4000 or 5200 mg/kg bw.
Rats were observed for 14 days. For all rats body weights were measured
and a gross necropsy was performed at the end of the observation period.
related clinical signs included hunched post mortem abnormal gait,
ataxia and lethargy in the majority of animals dose at all levels. Group
mean body weight gains were not affected. Mortality was observed in
males dosed at 2000 mg/kg bw and above an in females dosed at 3200 mg/kg
bw and above. No abnormalities were recorded at necropsy.
endpoint conclusion was that the rat acute oral LD50 was >2000 mg/kg bw
in males and females. Therefore, according to Annex I for Regulation
(EC) 1272/2008 the active ingredient, 1,9-Nonanediol has no obligatory
labelling requirement for acute oral toxicity and is unclassified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again