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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
1941
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Acceptable publication which meets basic scientific principles, however study was a preparative study, not a main study.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1951

Materials and methods

Principles of method if other than guideline:
Preliminary test
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Dichloroacetic acid
EC Number:
201-207-0
EC Name:
Dichloroacetic acid
Cas Number:
79-43-6
Molecular formula:
C2H2Cl2O2
IUPAC Name:
2,2-dichloroacetic acid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Duration of exposure:
8 h
Control animals:
not specified

Results and discussion

Mortality:
not letal

Applicant's summary and conclusion

Conclusions:
Maximum saturated vapor inhalation (Dichloroacetic acid) for no death by rats was 8 hours.
Executive summary:

The maximum exposure time to saturated vapor inhalation (Dichloroacetic acid) by rats was 8 hours.