Salicylamide

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08-Jun-2010 to 20-Aug-2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted in compliance with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive and done to a valid guideline.

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

GLP compliance:

no

Type of method:

gas saturation method

Temp.:

25 °C

Vapour pressure:

0.002 Pa

Remarks on result:

other: interpolated value

Temp.:

20 °C

Vapour pressure:

0.001 Pa

Remarks on result:

other: measured value

Temp.:

30 °C

Vapour pressure:

0.004 Pa

Remarks on result:

other: measured value

Temp.:

40 °C

Vapour pressure:

0.016 Pa

Remarks on result:

other: measured value

Transition / decomposition:

no

 

Results of the Vapor Pressure Determination

Column No.	Temp.	Volume* V2	Amount of test item in trap 1	Amount of test item in trap 2	Total amount of test item	Vapor pressure	Average vapor pressure
	[°C]	[mL]	[µg]	[µg]	[µg]	[Pa]	[Pa]
1	20.1	249060	13.140	0.000	13.140	9.4 x 10^-4	9.7 x 10^-4
2		320787	19.473	0.000	19.473	1.1 x 10^-3
3		388851	19.814	0.000	19.814	9.1 x 10^-4
1	30.2	67934	15.092	0.530	15.622	4.2 x 10^-3	4.2 x 10^-3
2		78835	17.496	0.000	17.496	4.1 x 10^-3
3		102965	23.816	0.000	23.816	4.3 x 10^-3
1	39.8	53331	44.824	0.000	44.824	1.6 x 10^-2	1.6 x 10^-2
2		68191	56.287	0.000	56.287	1.6 x 10^-2
3		81830	68.166	0.000	68.166	1.6 x 10^-2

*       Corrected volume at test temperature as calculated under “Volume correction”

Conclusions:

Calculation of the vapor pressure at 25 °C by interpolation based upon the simplified Clausius-Clapeyron equation resulted in a vapor pressure of 2.0 x 10 E-3 Pa at 25 °C.

Executive summary:

During this study, the vapor pressure of the test item has been determined using the gas saturation method. The vapor pressure of salicylamide was measured at test temperatures of 20 °C, 30 °C and 40 °C and was determined to be 9.7 x 10^-4Pa at 20 °C, 4.2 x 10^-3Pa at 30 °C, 1.6 x 10^-2Pa at 40 °C. The vapor pressure at 25 °C was interpolated from the vapor pressure curve and was calculated to be 2.0 x 10^-3Pa at 25 °C.

Description of key information

0.0020 Pa, 25°C, OECD 104, gas saturation, Weissenfeld 2010

Key value for chemical safety assessment

Vapour pressure:

0.002 Pa

at the temperature of:

25 °C

Additional information

A recent guideline study is available which is considered to be reliable and adequate, and is carried forward for use in risk assessment, classification and labelling.