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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08-Jun-2010 to 20-Aug-2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted in compliance with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive and done to a valid guideline.
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
no
Type of method:
gas saturation method
Temp.:
25 °C
Vapour pressure:
0.002 Pa
Remarks on result:
other: interpolated value
Temp.:
20 °C
Vapour pressure:
0.001 Pa
Remarks on result:
other: measured value
Temp.:
30 °C
Vapour pressure:
0.004 Pa
Remarks on result:
other: measured value
Temp.:
40 °C
Vapour pressure:
0.016 Pa
Remarks on result:
other: measured value
Transition / decomposition:
no

 

Results of the Vapor Pressure Determination

Column No.

Temp.

Volume*
V2

Amount of test item in trap 1

Amount of test item in trap 2

Total amount of test item

Vapor pressure

Average vapor pressure

 

[°C]

[mL]

[µg]

[µg]

[µg]

[Pa]

[Pa]

1

20.1

249060

13.140

0.000

13.140

9.4 x 10-4

9.7 x 10-4

2

320787

19.473

0.000

19.473

1.1 x 10-3

3

388851

19.814

0.000

19.814

9.1 x 10-4

1

30.2

67934

15.092

0.530

15.622

4.2 x 10-3

4.2 x 10-3

2

78835

17.496

0.000

17.496

4.1 x 10-3

3

102965

23.816

0.000

23.816

4.3 x 10-3

1

39.8

53331

44.824

0.000

44.824

1.6 x 10-2

1.6 x 10-2

2

68191

56.287

0.000

56.287

1.6 x 10-2

3

81830

68.166

0.000

68.166

1.6 x 10-2

*       Corrected volume at test temperature as calculated under “Volume correction”
Conclusions:
Calculation of the vapor pressure at 25 °C by interpolation based upon the simplified Clausius-Clapeyron equation resulted in a vapor pressure of 2.0 x 10 E-3 Pa at 25 °C.
Executive summary:

During this study, the vapor pressure of the test item has been determined using the gas saturation method. The vapor pressure of salicylamide was measured at test temperatures of 20 °C, 30 °C and 40 °C and was determined to be 9.7 x 10-4Pa at 20 °C, 4.2 x 10-3Pa at 30 °C, 1.6 x 10-2Pa at 40 °C. The vapor pressure at 25 °C was interpolated from the vapor pressure curve and was calculated to be 2.0 x 10-3Pa at 25 °C.

Description of key information

0.0020 Pa, 25°C, OECD 104, gas saturation, Weissenfeld 2010

Key value for chemical safety assessment

Vapour pressure:
0.002 Pa
at the temperature of:
25 °C

Additional information

A recent guideline study is available which is considered to be reliable and adequate, and is carried forward for use in risk assessment, classification and labelling.