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EC number: 287-502-5
CAS number: 85536-20-5
repeated dose toxicity of technical grade mixed xylenes was investigated
in male and female Sprague-Dawley rats following oral gavage
administration for 90 days at 0, 150, 750 or 1500 mg/kg/day.
Treatment-related alterations were mild and limited primarily to
increased relative liver weight (LOAEL 150 mg/kg bw/d for males; NOAEL
150 mg/kg bw/d for females; no histopathological alterations), relative
kidney weight (higher LOAELs and NOAELs) and a reduction in body weight
gain (males, NOAEL 750 mg/kg/d).
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