Registration Dossier
Registration Dossier
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EC number: 287-502-5 | CAS number: 85536-20-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The lowest result is a 24 hour EC50 of 1mg/l for o-xylene.
Key value for chemical safety assessment
Additional information
Data is available on the acute toxicity of each of the xylene isomers and ethylbenzene to aquatic invertebrates. The study by Galassiet al(1988) follows OECD 202 and usesDaphnia magna, whilst Holcombeet al(1987) used a flow through system to expose different species (includingDaphnia magna) simultaneously. Niederlehneret al(1998) usedCeriodaphnia dubiaas the test organism. All studies included analytical confirmation of the exposure concentrations.
The 24 and 48 hour EC50 results reported from these studies for the different isomers and ethylbenzene are very similar, with a range of 1 - 4.7mg/l. In the study by Niederlehneret al(1998) the highest concentration tested did not result in effects on mortality, so the EC50 is >3.4 mg/l. The most conservative result from the individual isomers will be used in the risk assessment.
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