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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from handbook, authoritative and modeling databases
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Determination of octanol water partition coefficient of the test substance (2-methoxyphenyl)methanol.
GLP compliance:
not specified
Type of method:
other: No data available
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
- Name (IUPAC name): (2-methoxyphenyl)methanol
- Common name: 2-Methoxybenzyl alcohol
- Molecular formula: C8H10O2
- Molecular weight: 136.165 mg/l
- Smiles:O(c1c(cccc1)CO)C
- InChI:1S/C8H10O2/c1-10-8-5-3-2-4-7(8)6-9/h2-5,9H,6H2,1H3
- Substance type:Organic
- Physical state: Liquid
Key result
Type:
log Pow
Partition coefficient:
1.13
Remarks on result:
other: Other details not known
Details on results:
The logKow of test chemical (2-methoxyphenyl)methanol was determined to be 1.13.
Conclusions:
The partition coefficient (log Pow) value of the substance (2-methoxyphenyl)methanol was determined to be 1.13.
Executive summary:

The partition coefficient (log Pow) value of the substance (2-methoxyphenyl)methanol was determined to be 1.13. Based on the experimental value, chemical (2-methoxyphenyl)methanol can be considered to be hydrophilic in nature.

Description of key information

Based on the available data from handbook, authoritative and modelling databases, the partition coefficient (log Pow) value of the substance (2-methoxyphenyl)methanol was determined to be 1.13. Based on the experimental value, chemical (2-methoxyphenyl)methanol can be considered to be hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.13

Additional information

Based on the available data in a key studyfrom handbook, authoritative and modelling databases, the partition coefficient (log Pow) value of the substance (2-methoxyphenyl)methanol was determined to be 1.13.

In a supportingstudy from peer reviewed journal,the partition coefficient (log Pow) value of the substance (2 -methoxyphenyl)methanol was estimated to be 1.16.

In an another supportingstudy from secondary source,the partition coefficient (log Pow) value of the substance (2 -methoxyphenyl)methanol was determined to be 1.13.

Additional studyfrom predicted database indicates that the octanol waterpartition coefficient (log Pow) value of the substance (2 -methoxyphenyl)methanol was estimated to be 1.144 at 25°C.

Thus, based on the available information, the logPow valueof the test substance (2 -methoxyphenyl)methanol ranges from 1.13 to 1.16, respectively. On the basis of this value, chemical (2 -methoxyphenyl)methanol be considered to be hydrophilic in nature.