(2S)-1-isopropoxy-1-oxopropan-2-yl pivalate

Flash point

Link to relevant study record(s)

Reference

Endpoint:

flash point of flammable liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014-03-11

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to EC/ISO guideline, and under GLP. No deviation was reported. Test substance is adequately specified with purity. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

EU Method A.9 (Flash-Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

ISO 2719 (Determination of flash point - Pensky-Martens closed cup method)

Version / remarks:

2002

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.6315 (Flammability)

Deviations:

no

Qualifier:

according to guideline

Guideline:

ISO No., other: CIPAC MT 12

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

inspected on January 22 and 23, 2013 / signed on March 22, 2013

Type of method:

closed cup

Flash point apparatus:

Pensky-Martens apparatus

Flash point:

84.42 °C

Atm. press.:

1 016.45 hPa

Remarks on result:

other: measured value

Key result

Flash point:

84 °C

Atm. press.:

1 013 hPa

Remarks on result:

other: corrected to normal atmP

Preliminary test:

The results of the pre-test with the search program are summarised in the following table. An ignition is indicated by + and no ignition by -.

Table 4.11/1: Preliminary test

Amount of test item (g)	Temperature (°C)	Ignition (+/-)	Air pressure (hPa)	Comments
70.10	< 88.0	+	1016.4	---

 In the preliminary test the lowest temperature where an ignition was observed was < 88.0 °C.

Main test:

The results of the main test are summarised in the following table. An ignition is indicated by + and no ignition by -.

 Table 4.11/2: Main test

Amount of test item (g)	Temperature (°C)	Ignition (+/-)	Air pressure (hPa)	Corrected flash point (°C)
64.79	84.0	+	1016.4	83.92
63.38	85.0	+	1016.5	84.91

The corrected mean value of both measured flash points to standard pressure is 84.42°C. The resulting average corrected flash point rounded down to the nearest multiple of 0.5°C is 84.0 °C.

Interpretation of results:

Category 4 (combustible liquids) based on GHS criteria

Remarks:

EU-CLP criteria not met

Conclusions:

The substance is NOT classified as flammable liquid according to CLP criteria (>60°C).
GHS Flam.Liq.4 (< 93°C).

Executive summary:

The flash point of the test substance was determined under GLP according to ISO 2719 (listed in EU guideline), using a closed cup equilibrium method. The measured value was corrected to normal atmospheric pressure.

The normal flash point of test substance has been determined to be 84°C.

Description of key information

The substance is NOT classified as flammable liquid according to Regulation (EC) N°1272/2008 (CLP) criteria.
 The substance is classified as FLAMMABLE LIQUID category 4 according to UN GHS criteria. 

Key value for chemical safety assessment

Flash point at 101 325 Pa:

84 °C

Additional information

A fully reliable experimental study, conducted according to a recognized EC/ISO method (closed cup), is available. It is considered as a key study, and the result is retained as key data.

This study is relevant for the classification regarding flammable properties.