Sulfuric Acid, waste gas washing, copper smelting

Acute Toxicity: dermal

Administrative data

Endpoint:

acute toxicity: dermal

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: no GLP (but other Quality Assurance); software

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

other: software

Title:

Unnamed

Year:

2010

Materials and methods

Principles of method if other than guideline:

Acute (dermal) toxicity of the UVCB substance was determined by classifying based on Mixture rules from EU CLP (summation and/or additivity of classified components to derive Hazard class) and back calculation to the corresponding Acute (oral) Toxicity criteria

GLP compliance:

no

Remarks:

(equivalent Quality assurance)

Test type:

other: CLP calculation software

Test material

Test material information

Constituent 1

Reference substance name:

sulfuric acid hydrate

EC Number:

922-670-1

IUPAC Name:

sulfuric acid hydrate

Details on test material:

Worst case (maximum across industry) as in iu 1.2;
See IUCLID Section 1.4, for company specific elemental composition; and representative sample for mineralogical information (IUCLID Section 4.23 -Outotec report)

Results and discussion

Effect levels

Dose descriptor:

other:

Effect level:

>= 2 000 other: ATE (mg/kg bodyweigth)

Based on:

dissolved

Remarks on result:

other: prediction

Any other information on results incl. tables

 The calculated classification via Additivity method (lower Tier Arche CLP Tool) resulted in a Classification "Acute (dermal): not classified" for the UVCB substance Copper Slime (toxicity of all metal constituents > 1% w/w is known, from 1st ATP CLP + all assessed metals).

Based on this result, the related criteria provided the estimated value for acute (dermal) toxicity: Acute Toxicity Estimate >2000 mg/kg bodyweight.

Applicant's summary and conclusion

Interpretation of results:

not classified

Remarks:

Migrated information Criteria used for interpretation of results: other: EU CLP mixture toxicity rules

Conclusions:

Good quality study that can be used to predict a ATE of the UVCB substance. Note: toxicities of constituents/species as of 1st ATP CLP + assessed metals

Executive summary:

The study provided an estimate of the Acute (dermal) toxicity, derived on basis of the Classification outcome (Mixture toxicity rules, no acute dermal toxicity = no dermal toxicity) from the UVCB (max across industry) as defined in IUCLID section 1.2/1.4/4.23. The result is applicable to all sulfuric acid, waste gas cooling and cleaning, copper smelting that fall under the defined concentration ranges (IUCLID section 1.2).