Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 922-670-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: automatic calculation tool in development at Eurometaux
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- other: software
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
- Principles of method if other than guideline:
- Aquatic toxicity of the UVCB substance was determined by classifying based on Mixture rules from EU CLP (Lower Tier= summation of classified components to derive Hazard class) and back calculation to the corresponding L(E)C50 range.
- GLP compliance:
- not specified
- Remarks:
- other Quality Assurance was applied
Test material
- Reference substance name:
- sulfuric acid hydrate
- EC Number:
- 922-670-1
- IUPAC Name:
- sulfuric acid hydrate
- Details on test material:
- Worst Case: maximum across industry, as defined in IUCLID Section 1.2;
see IUCLID Section 1.4, for company specific elemental composition; and representative sample for mineralogical information (IUCLID Section 4.23 -Outotec report)
Representative copper speiss - randomly collected from production over long period, crushed and homogenised
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- <= 1 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- dissolved
- Basis for effect:
- not specified
Any other information on results incl. tables
The calculated classification via Summation method (lower Tier Arche CLP Tool) resulted in an "Acute Chronic Category 1" classification for the UVCB substance
Based on this result, the related criteria provided the estimated value for acute (short term) toxicity to aquatic invertebrate (see EU CLP Guidance Annex I Table 4.1.0): 48hr EC50 (for crustacea) < or equal 1 mg/l.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Result can be used to predict EC50 for crustacea and classify the UVCB substance as Acute chronic 1 H 410 (N;R50-53).
- Executive summary:
The study provided a conservative estimate of the EC50 (for crustacea), derived on basis of the Classification outcome (Mixture toxicity rules) from a Worst Case (max across industry) as defined in IUCLID section 1.4/4.23. The result is applicable to all Sulphuric acid, copper smelting that fall under the defined concentration ranges (IUCLID section 1.2).
Validity of the model used:
- defined end points: aquatic toxicity (acute & chronic)
- unambiguous algorithm from EU CLP Guidance: summation/additivity formula to determine Classification and, back-calculation to related hazard criteria
- Applicability domain: applicable to classify complex metal containing materials in a Tiered approach (see EU CLP Guidance pg 499 Annex IV.5.5, and for conceptual outline ICMM Fact Sheet “Ores & Concentrates –An industry approach to EU hazard classification”, Nov 2009). Available input information: elemental composition and representative mineralogical information (lower Tier, no correction for bio availability).
- Mechanistic interpretation - metal species: the tool translates the elemental composition into a mineralogical composition relevant for classification (ie distribution pattern for each element/constituent of the UVCB substance). In the Lower Tier, the classification is derived (by means of the Sum formula) without taking into account any bio availability correction. Mechanistic interpretation - metal-ion additivity: (1) The additivity assumption for the toxicity of mixtures of metals was evaluated by De Schamphelaere (2009) - in JAB Bass et al. in "Environmental Quality Standards for trace metals in the aquatic environment" , UK Environment Science Report 2009 (Appendix 2): No clear conclusions could be made from the literature review but a targeted experimental design with aquatic algae, showed that the additivity mode could predict the toxicity of metal mixture: the toxicity of simultaneous Cu, Zn, Ni, Cd and Pb additions to two distinct surface waters could be predicted by the additive toxic unit approach. (2) A. Stockdale, E Tipping, S Lofts & SJ Ormod, combined metal speciation to the additive toxicity approach and predicted the combined metal toxicity in a range of UK river systems impacted by metals : in "Modelling multiple metal toxic effects in the field - evaluation of the Toxicity Binding Model (TBM)", ICA Report November 2009.
Adequacy of prediction: the substance falls within the applicability domain described above and, therefore, the predicted value can be considered as reliable. The prediction is moreover conservative as the Lower Tier approach was used (ie elemental composition + mineralogy is known, no T/D available). Same conclusions apply to the prediction of the Aquatic toxicity value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.