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Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-03-04 – 2017-03-04
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental result performed using standard methods of analysis
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Principles of method if other than guideline:
The melting point determination of Test item 4-nitro-o-toluidine (CAS No. 99-52-5 ) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block.
GLP compliance:
not specified
Type of method:
other: standard laboratory method
Specific details on test material used for the study:
- Name of test material (as cited in study report): 2-methyl-4-nitroaniline
- Molecular formula: C7 H8 N2 O2
- Molecular weight: 152.152 g/mol
- Smiles notation: c1(cc(c(N)cc1)C)[N+](=O)[O-]
- InChI: 1S/C7H8N2O2/c1-5-4-6(9(10)11)2-3-7(5)8/h2-4H,8H2,1H3
- Substance type: Organic
- Physical state: Solid
Key result
Melting / freezing pt.:
>= 128.6 - <= 130.6 °C
Atm. press.:
972.5 hPa
Decomposition:
no
Sublimation:
no
Remarks on result:
other: other details not available
Conclusions:
The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa.
Executive summary:

The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa.

Description of key information

The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
128.6 °C

Additional information

The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa

Other supporting studies from various reliable sources such as authoritative database and handbooks,the melting point chemical 2-methyl-4-nitroaniline was determined to be in the range of 128 degree C to 133.5 degree C.

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of melting point temperature as 128.6 degree C thus considered as key study for the chemical safety assessment.