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EC number: 202-762-1 | CAS number: 99-52-5
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-03-04 – 2017-03-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Experimental result performed using standard methods of analysis
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Principles of method if other than guideline:
- The melting point determination of Test item 4-nitro-o-toluidine (CAS No. 99-52-5 ) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block.
- GLP compliance:
- not specified
- Type of method:
- other: standard laboratory method
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 2-methyl-4-nitroaniline
- Molecular formula: C7 H8 N2 O2
- Molecular weight: 152.152 g/mol
- Smiles notation: c1(cc(c(N)cc1)C)[N+](=O)[O-]
- InChI: 1S/C7H8N2O2/c1-5-4-6(9(10)11)2-3-7(5)8/h2-4H,8H2,1H3
- Substance type: Organic
- Physical state: Solid - Key result
- Melting / freezing pt.:
- >= 128.6 - <= 130.6 °C
- Atm. press.:
- 972.5 hPa
- Decomposition:
- no
- Sublimation:
- no
- Remarks on result:
- other: other details not available
- Conclusions:
- The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa.
- Executive summary:
The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa.
Reference
Description of key information
The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 128.6 °C
Additional information
The melting point determination of 2-methyl-4-nitroaniline (CAS No. 99-52-5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was found to be 128.6- 130.6°C at 972.5hPa
Other supporting studies from various reliable sources such as authoritative database and handbooks,the melting point chemical 2-methyl-4-nitroaniline was determined to be in the range of 128 degree C to 133.5 degree C.
As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of melting point temperature as 128.6 degree C thus considered as key study for the chemical safety assessment.
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