Registration Dossier
Registration Dossier
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EC number: 201-678-2 | CAS number: 86-52-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1967
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: collection of data, but record lacks methodological details
Data source
Reference
- Reference Type:
- other: Database
- Title:
- RTECS (Registry of Toxic Effects of Chemical Substances)
- Year:
- 2 016
- Bibliographic source:
- IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin (Pittsburgh, PA) 1947-69.
Materials and methods
- Principles of method if other than guideline:
- no data on guideline, Study period lies before the acceptance of guidelines
- GLP compliance:
- not specified
- Remarks:
- Data retrieval was performed in 2016 by using RTECS. Toxicity values without further details are given. The cited reference lacks information on GLP compliance and year of study.
- Test type:
- other: no data, but probable standard acute method
Test material
- Reference substance name:
- 1-(chloromethyl)naphthalene
- EC Number:
- 201-678-2
- EC Name:
- 1-(chloromethyl)naphthalene
- Cas Number:
- 86-52-2
- Molecular formula:
- C11H9Cl
- IUPAC Name:
- 1-(chloromethyl)naphthalene
- Test material form:
- not specified
Constituent 1
- Specific details on test material used for the study:
- no specific details given
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Key result
- Dose descriptor:
- LD50
- Effect level:
- ca. 890 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Executive summary:
Acute toxicity oral in rat was reported in RTECS as LD50 890 mg/kg,
Toxicity data reference: Industrial Hygiene Foundation of America, Chemical and Toxicilogical Series, Bulletin (Pittburgh, Pa) 1947 -69
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