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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1967
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: collection of data, but record lacks methodological details

Data source

Reference
Reference Type:
other: Database
Title:
RTECS (Registry of Toxic Effects of Chemical Substances)
Year:
2016
Bibliographic source:
IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin (Pittsburgh, PA) 1947-69.

Materials and methods

Principles of method if other than guideline:
Probably standard dermal toxicity study
GLP compliance:
not specified
Remarks:
Data retrieval was performed in 2016 by using RTECS. Toxicity values without further details are given. The cited reference lacks information on GLP compliance and year of study.
Test type:
standard acute method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
not specified
Specific details on test material used for the study:
no data given

Test animals

Species:
rabbit

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
ca. 2 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria
Executive summary:

Acute toxicity dermal in rabbit was reported as LD50 2000 mg/kg.

Toxicity data reference: Industrial Hygiene Foundation of America, Chemical and Toxicilogical Series, Bulletin (Pittburgh, Pa) 1947