Registration Dossier
Registration Dossier
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EC number: 279-365-5 | CAS number: 80010-51-1
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 27 Oct 2015 to 12 Nov 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Identification: FAT 21036/G TE Lot: AT-0033945200
Appearance: Dark blue powder - Key result
- Water solubility:
- 64.3 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 20 g/L
- Temp.:
- 20 °C
- Remarks on result:
- other: pH is not available
- Details on results:
- The preliminary visual experiments showed that the water solubility of the test item is between 20 and 100 g/l.
- Conclusions:
- The water solubility of the test item at a temperature of 20 °C was determined to be 64.3 g/L.
- Executive summary:
The water solubility of FAT 21036/G was evaluated in a study conducted according to EU Method A.6 and OECD Guideline 105. Flask method was used for this purpose. Based on the findings of the study, the water solubility of FAT 21036/G at 20 °C was determined to be 64.3 g/L.
Reference
Preliminary Visual Estimation of the Water Solubility
Amount of the test item in mg |
Total volume in ml |
Appearance of mixture |
1000 |
1 |
undissolved |
10 |
undissolved |
|
50 |
dissolved |
The preliminary visual experiments showed that the water solubility of the test item is between 20 and 100 g/L
Flask-Method
Experiment |
A |
B |
C |
D (blank) |
Amount of test item [mg] |
1000 |
1000 |
1000 |
- |
Stirring time at 30 °C [h] |
24 |
48 |
72 |
72 |
Measured concentration [mg/L] |
15.4 |
12.9 |
19.9 |
- |
Dilution |
0.01/10-1/4 |
0.01/10-1/4 |
0.01/10-1/4 |
- |
Water solubility [g/L] |
61.6 |
51.6 |
79.7 |
- |
Average experiments A to C: 64.3 g/L
Recovery data:
Standard |
Measured Concentration (mg/l) |
% Recovery |
Sample C + 18.7 mg test item |
37.6 |
97.4 |
The recovery of 97.4 % indicates a sufficient accuracy of the analytical method.
Description of key information
The water solubility of FAT 21036/G was evaluated in a study conducted according to EU Method A.6 and OECD Guideline 105. Flask method was used for this purpose. Based on the findings of the study, the water solubility of FAT 21036/G at 20°C was determined to be 64.3 g/L.
Key value for chemical safety assessment
- Water solubility:
- 64.3 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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