P-1401

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

6 August 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

capillary method

Key result

Atm. press.:

1 017 hPa

Decomposition:

yes

Decomp. temp.:

200.8 °C

The preliminary study and measurements were performed under atmospheric pressure of 1017 hPa. In order to determine the melting temperature range for PRODUCT P-1401, the preliminary study was carried out in the temperature range: 30.0 °C – 200.0 °C. In the course of the study, darkening of the test item was observed (about 200.0 °C, gradient temperature – 20.0 °C/min). The study was repeated for the three measurement series. Initially at the temperature of 71.4°C the samples started darkening (dark yellow), above 170° C the color of the samples were brown. About 200 °C the structures of the samples were disturbed (the samples shrank) and the gaseous products were observed (some bubbles). The samples were dark brown. No melting point was visually observed up to the end of heating: 400 °C, when the final color was deep brown/graphite. It is suggested that all samples started to decompose about 200.8 °C (gradient temperature: 0.5 °C/min). The accuracy of the apparatus is defined as: up to 250.0 °C is equal to 0.3 °C, 250.0 - 400.0 °C is equal to 0.3 °C - 0.5 °C). In this study, the accuracy of the apparatus was equal to 0.3 °C.

Sample darkening

Sample	Decomposition temperatura ºC
1	71.3
2	71.3
3	71.7
Average values and standard deviations ºC	71.4±0.2

Decomposition temperature

Sample	Decomposition temperatura ºC
1	200.4
2	200.8
3	201.2
Average values and standard deviations ºC	200.8±0.4

Conclusions:

The decomposition of the test item was observed at a temperature of 200.8 °C and 1017 hPa. No melting temperature was observed up to 400 ºC.

Executive summary:

The determination of the melting point was performed according to the OECD Guideline 201 (GLP study). The capillary tube in heated metal block method and BÜCHI Melting Point M-565 apparatus was used. The decomposition of the test item was observed at a temperature of 200.8 °C and 1017 hPa. No melting temperature was observed up to 400 ºC.

Description of key information

Key study: Test method OECD Guideline 201. GLP study. The decomposition of the test item was observed at a temperature of 200.8 °C and 1017 hPa. No melting temperature was observed up to 400 ºC.

Additional information

Key study: The determination of the melting point was performed according to the OECD Guideline 201 (GLP study). The decomposition of the test item was observed at a temperature of 200.8 °C and 1017 hPa. No melting temperature was observed up to 400 ºC.