Registration Dossier

Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC estimation method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Test temperature:
room temperature

HPLC method

Details on study design: HPLC method:
The selection of the test system is based on the guidelines. HPLC is a useful method for estimation of the adsorption coefficient Koc. The Koc indicates the binding capacity of the test item on soil or sewage sludge and allows to compare the adsorption behaviour of different chemicals.

HPLC, UV-detection; YMC-Pack Cyano CN 125052504 QT, 250x4.0 mm, mobile phase: Methanol: 0.01 mol/l citrate buffer pH 6 (55:45 (v/v);

Results and discussion

Adsorption coefficientopen allclose all
Type:
Koc
Value:
0.066
Type:
log Koc
Value:
-1.18

Results: HPLC method

Details on results (HPLC method):
Dead time of the HPLC-Sytem: 5.109 min.; Retention times of reference substances used for calibration: 2-Nitrobenzamid: 7.4 min; log Koc 1.45; Aniline: 8.0 min, log Koc 2.07; Phenyl benzoate: 15.7 min, log Koc: 7.87;
Parazophos: 24.8 min, log Koc 3.65; Phenanthrene: 25.5 min, log Koc 4.09; 4,4`-DDT: 72 min, log Koc 5.63; test substance: 5.37 min

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The substance has no relevant adsorptive potential.