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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

biodegradation in water: ready biodegradability
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Study period:
Not specified.
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study according to international guidelines but non-GLP and limited information about test conditions.
according to guideline
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
not specified
GLP compliance:
Oxygen conditions:
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Details on inoculum:
- Contained 29.9 mg/L suspended solids.
- Aerated for 24 h before the start of the expsoure of the substance.
Duration of test (contact time):
28 d
Initial conc.:
40 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Details on study design:
Test was performed in duplicate. Simultanious tests with a reference substance and an untreated control were included.
Reference substance:
benzoic acid, sodium salt
Preliminary study:
Not applicable
Key result
% degradation (O2 consumption)
Sampling time:
28 d
Details on results:
lag phase: 2 days
10-day window: d 2 - d 12
% degradation 10-day window: 70
% degradation after 28 days (mean): 82.2
Validity criteria fulfilled:
Oxygen uptake of blank < 60 mg/L (34.8 mg/L); Difference between replicates of the test tchemical less than 20%; Percentage of degradation of the reference substance reached 60% before day 14.
Interpretation of results:
readily biodegradable
A combination of dodecyl and tridecyl lactates, linear and branched, proved to be readily biodegradable in an aerobic degradation test.

Description of key information

A combination of dodecyl and tridecyl lactates, linear and branched, proved to be readily biodegradable in an aerobic degradation test. Supporting test with other alkyl lactates confirm the high potential for biodegradation of the product for registration.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information