Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 300-338-1
CAS number: 93925-36-1
The acute oral LD50 of CERAPHYL® 41 was 21 ml/kg bodyweight in rats.
Twenty five Wistar albino rats (3 male, 2 female/group) were dosed
orally with CERAPHYL® 41 at 2.5, 5, 10, 20 and 40 ml/kg bodyweight.
Animals were observed daily for mortality for 14 days. Four animals in
the 40 ml/kg group died. One animal in the 10 ml/kg group died.
Inhalation Toxicity ofLactate
Esters in Rats:
4 -h LC50 (mg/m3)
During exposure decrease in breathing rates and wet nares; Wet fur postexposure; Gross necropsy revealed 7 of 10 with grayish lungs; two lungs had irregular surfaces
During exposure decrease in breathing rates; piloerection; wet nares; lachrymation; Gross necropsy revealed pale lungs with spots
During exposure decrease in breathing rates and wet head and fur; No gross necropsy changes;
During exposure decrease in breathing rates; piloerection; hunched appearance; Postexposure: Apnea; No gross necropsy changes
During exposure decrease in breathing rates and wet head and fur; Wet fur, sniffing, and slow movement postexposure; Gross necropsy revealed 1 of 10 with pale lungs
During exposure increase in breathing rates, irregular breathing patterns and wet nares and fur; Gross necropsy revealed rusty brown lungs in two females
Ceraphyl 41 containing C12-C15 lactates has an oral LD50 of 20,000 mg/kg
and the inhalation LC50 of lactate esters is generally above 5000 mg/m3.
Also dermal exposure to C12 -C13 alkyl lactates appears to be
The data are conclusive but not sufficient for classification. This is
because the acute toxicity estimates (ATEs) exceed the upper limits for
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again