Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Remarks:
Type of genotoxicity: chromosome aberration
Type of information:
experimental study planned
Study period:
Six months after ECHAs final decision.

Data source

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
Qualifier:
according to guideline
Guideline:
EU Method B.12 (Mutagenicity - In Vivo Mammalian Erythrocyte Micronucleus Test)
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 489: In Vivo Mammalian Alkaline Comet Assay
Type of assay:
micronucleus assay

Test material

Constituent 1
Chemical structure
Reference substance name:
[5-acetyl-2-(acetyloxy)phenyl]methyl acetate
EC Number:
921-042-4
Cas Number:
24085-06-1
Molecular formula:
C13-H14-O5
IUPAC Name:
[5-acetyl-2-(acetyloxy)phenyl]methyl acetate

Test animals

Species:
rat

Results and discussion

Applicant's summary and conclusion