(R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

July 1994 - February 1995

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Deviations:

yes

Remarks:

the result for the test item is the mean value of 6 tests, maximum value not specified.

GLP compliance:

yes

Contact with:

powdered cellulose

Key result

Sample tested:

test mixture as specified

Remarks:

3:2 sample-to-cellulose ratio

Parameter:

maximum burning rate

Result:

0.93 mm/s

Remarks on result:

other: Maximum burning rate of the test substance/combustible substance mixture

Remarks:

(mean value of 6 tests)

Key result

Sample tested:

reference mixture as specified

Remarks:

3:2 barium nitrate to cellulose ratio

Parameter:

maximum burning rate

Result:

1.22 mm/s

Table 1. Results of the determination of oxidising properties.

Mixture composition (% w/w)			Burning rate (mm/s)
TS	CS	RS
10	90	-	No flame propagation
20	80	-	No flame propagation
30	70	-	No flame propagation
40	60	-	No flame propagation
50	50	-	No flame propagation
60	40	-	0.93 (mean value of 6 tests)
70	30	-	No flame propagation
80	20	-	No flame propagation
90	10	-	No flame propagation
-	30	70	0.58
-	40	60	1.22
-	50	50	0.93
-	70	30	0.58

Interpretation of results:

GHS criteria not met

Conclusions:

The test substance does not have oxidising properties.

Executive summary:

The oxidising properties test was carried out according to EU Method A 17.

The maximum burning rate of the test substance/combustible substance mixtures (0.93 mm/s) is lower than the maximum burning rate of reference substance/combustible substance mixtures (1.22 mm/s), therefore the Fosfomycin PEA salt can be considered not having oxidizing properties.

Description of key information

Key study: Test method according to EU Method A.17. GLP study.

The test substance was considered to be non-oxidizing.

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Additional information

Key study: Test method according to EU Method A 17. GLP study. The maximum burning rate of the test substance/combustible substance mixtures (0.93 mm/s) is lower than the maximum burning rate of reference substance/combustible substance mixtures (1.22 mm/s), therefore, the test substance was considered not having oxidizing properties.

Justification for classification or non-classification

Based on the available information on oxidising properties, the test substance is considered to be non-oxidizing, and therefore, the substance is not classified.