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Surface tension

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Reference
Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 1994 - February 1995
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.5 (Surface Tension)
Deviations:
no
GLP compliance:
yes
Type of method:
ring method
Key result
Surface tension:
71.05 mN/m
Temp.:
20 °C
Conc.:
1 g/L
Remarks on result:
other: Experimental mean: 70.42 mN/m. Calibration factor: 1.0090. Stand. Dev.: 0.02.

Table 1. Surface tension determination. 

Test No.

Surface tension

at 20 ± 0.5 ºC

(mN/m)

1

70.45

2

70.43

3

70.42

4

70.42

5

70.42

6

70.41

7

70.40

8

70.40

9

70.40

10

70.40

Mean value

70.42

SD

0.02

Corrected mean*

71.05

* mean x calibration factor (1.0090).

Conclusions:
Surface tension: 71.05 mN/m at 20 ºC
Executive summary:

The ring method was applied (EU Method A.5) for the measurement of the surface tension.

The surface tension of Fosfomycin PEA salt is 71.05 mN/m at 20 ºC (concentration of 1 g/L), with a standard deviation of 0.02.

Description of key information

Key study: Test method according to EU Method A.5. GLP study.

Key value for chemical safety assessment

Surface tension:
71.05
in mN/m at 20°C and concentration in mg/L:
1 000

Additional information

Key study: Test method according to EU Method A.5 (the ring method). GLP study. The surface tension of Fosfomycin PEA salt was 71.05 mN/m at 20 ºC (concentration of 1 g/L), with a standard deviation of 0.02.