Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

BIOACCUMULATION IN FRESHWATER, MARINE WATER, FRESHWATER AND MARINE SEDIMENT AND SOIL

The registration substance has a measured Log Kow of 3.3 and therefore a low to moderate potential for bioconcentration can be expected based on this screening criteria. In addition the 'B' Screening criteria of the vPvB / PBT Assessment of Log Kow >= 4.5 is not fulfilled.

As the registration substance has ester functions fast biotic ester cleavage will occur. In microorganisms rapid degradation has been found (see IUCLID Chapter 5.2.1) and rapid metabolism by higher organism could be shown in an in-vitro experiment with porcine lipases. (see IUCLID Chapter 7.1).

Furthermore the metabolic fate of polyglycerol fatty acid esters after administration is extensively investigated. (see IUCLID Chapter 7.1)

Overall the registration substance and the resulting metabolites are well known to metabolize rapidly and are eliminated fast.

Based on the measured Log Kow the Exposure modelling program EUSES 2.1 estimates a BCF fish of 127 L/kg wwt and a BCF earthworm of 24.8 L/kg wwt.

In addition calculations with EPA EPIWIN (v4.10) BCFBAF Program (v3.01) for all possible constituents showed a maximum for the Diglycerol-mono-C18-unsat-ester with Log BCF (regression-based estimate): 1.91 (BCF = 80.9 L/kg wet-wt) and Log BAF (Arnot-Gobas upper trophic): 1.23 (BAF = 17 L/kg wet-wt) which reflects the rapid metabolism. Results for all other constituents are below these values. All values are clearly <2000 L/kg wwt which is the definite criteria for PBT substances and clearly <5000 L/kg wwt which is the definite criteria for vPvB substances.

In result the registration substance has a low potential for bioaccumulation and measurement for bioaccumulation is therefore not warranted.