Propanamide, N-[4-(2,4-dihydroxyphenyl)-2-thiazolyl]-2-methyl-

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 Jan 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test O.1 (Test for oxidizing solids)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht, Mainz, Germany

Contact with:

powdered cellulose

Sample tested:

reference: 3:7 mixture potassium bromate + cellulose

Parameter:

mean burning time

Result:

96 s

Remarks on result:

flaming

Sample tested:

4:1 sample-to-cellulose ratio

Parameter:

mean burning time

Result:

290 s

Remarks on result:

flaming

Key result

Sample tested:

1:1 sample-to-cellulose ratio

Parameter:

mean burning time

Result:

313 s

Remarks on result:

flaming

Burning Times Reference Mixtures

In the following table, the measured data of the reference item mixtures is presented.

Ratio	Burning Times (mm:ss)
m/m	1	2	3	4	5	Mean
3:7	95	97	95	98	97	96

 

Burning Times Test Item Mixtures

In the following table, the measured data of the test item mixtures is presented.

Ratio	Burning Times (mm:ss)
m/m	1	2	3	4	5	Mean
4:1	296	285	296	294	277	290
1:1	319	305	322	310	308	313

 

Validity

The burning times of the reference mix were in the same dimension as stated in the table below. The burning times of the test item mixes are greater than 3 minutes.

Ratio m/m	Time given as Example in Guideline	Times Measured
3:7	100 s	95/97/95/98/97 s
2:3	54 s	not performed
3:2	4 s	not performed

 

Classification

The mixture the 4:1 ratio of test item N-[4-(2,4-dihydroxyphenyl)thiazol-2-yl]isobutyramide shows a shorter mean burning time than the 1:1 ratio.

The burning time means of all test item mixes were much greater than the burning times of the reference mixture with the ratio 3:7. Therefore, the study was terminated in accordance with the guidance on the application of the CLP criteria, decision logic 2.14 of GHS.

The test item is considered to have no oxidising properties. It should be classified as “not oxidizing” and “Not Division 5.1” following UN Handbook.

No observations arousing doubts concerning the accuracy of the results and the validity of the study were made.

Interpretation of results:

GHS criteria not met

Description of key information

The mixture the 4:1 ratio of test item N-[4-(2,4-dihydroxyphenyl)thiazol-2-yl]isobutyramide

shows a shorter mean burning time than the 1:1 ratio.

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Justification for classification or non-classification

The burning time means of all test item mixes were much greater than the burning times of

the reference mixture with the ratio 3:7.

The test item is considered to have no oxidising properties.