Propanamide, N-[4-(2,4-dihydroxyphenyl)-2-thiazolyl]-2-methyl-

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

18 - 21 Feb 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2014

Report date:

2014

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

GLP compliance:

yes (incl. QA statement)

Remarks:

Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht, Mainz, Germany

Type of method:

plate method

Test material

Test material information

Constituent 1

Reference substance name:

N-[4-(2,4-dihydroxyphenyl)-1,3-thiazol-2-yl]-2-methylpropanamide

EC Number:

807-621-3

Cas Number:

1428450-95-6

Molecular formula:

C13H14N2O3S

IUPAC Name:

N-[4-(2,4-dihydroxyphenyl)-1,3-thiazol-2-yl]-2-methylpropanamide

Test material form:

solid: particulate/powder

Results and discussion

Surface tension

Key result

Surface tension:

68.31 - 70.78 mN/m

Temp.:

20 °C

Conc.:

16.36 mg/L

Any other information on results incl. tables

The test item solution was held at constant temperature (20.0 ± 0.5 °C). 60 minutes after conclusion of the first measurement series, a second measurement series was performed for verification purposes. The following values were recorded:

Measured Values Test Item First Series

Measurement No.	Time /s	Mass /g	Surface Tension /mN/m	Temperature /°C
1	2.9	0.2874	70.11	19.9
2	5.8	0.2906	70.89	19.9
3	8.9	0.2905	70.87	19.9
4	11.8	0.2905	70.87	19.9
5	14.9	0.2906	70.89	19.9
6	17.8	0.2906	70.89	19.9
7	20.9	0.2905	70.87	19.9
8	23.8	0.2902	70.79	19.9
9	26.9	0.2902	70.79	19.9
10	29.8	0.2905	70.87	19.9
Mean			70.78
Standard Deviation			0.24

 

 

Measured Values Test Item Second Series

Measurement No.	Time /s	Mass /g	Surface Tension /mN/m	Temperature /°C
1	2.9	0.2745	66.96	20.2
2	5.9	0.2809	68.52	20.2
3	8.9	0.2802	68.35	20.2
4	11.9	0.2801	68.33	20.2
5	14.9	0.2806	68.45	20.2
6	17.9	0.2807	68.48	20.2
7	20.9	0.2809	68.52	20.2
8	23.9	0.2810	68.55	20.3
9	26.9	0.2806	68.45	20.2
10	29.9	0.2806	68.45	20.3
Mean			68.31
Standard Deviation			0.48

 

The concentration of the test item was calculated from the measured areas using the following equation:

Conc (x) = (Area (y) – a (-0.252185345) / b (1.70729314)

Calculated concentrations

Replicate	Sample Name	Calculated value in ppm
1	13111801G960 90%	16.38
2	13111801G960 90%	16.34
	Mean	16.36

 

The concentration in the 90% test solution was calculated with 16.36 mg/L

During the specified period of time, no relevant changes in the surface tension were detected. Values between 66.96 and 70.89 mN/m were recorded showing no relevant variations. As the determined surface tension of N-[4-(2,4-dihydroxyphenyl)thiazol-2-yl]isobutyramide was higher than 60 mN/m, the test item can be classified as not surface active.

 

Applicant's summary and conclusion

Conclusions:

not surface active

Executive summary:

not surface active