Triethoxy(3-isocyanatopropyl)silane

Melting point / freezing point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

2012-07-26 to 2012-08-01

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

30 May 2008

Deviations:

no

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

< -20 °C

Atm. press.:

1 013 hPa

Remarks on result:

other: No melting point was found between -150 and +50°C under these conditions. A glass transition was observed at -143°C.

The DSC measurements were performed twice. After cooling to -150°C at a rate of 2 K/min the sample was heated to 50°C at a rate of 5 K/min. The cooling as well as the heating curve show only a glass transition, indicating that the test item had solidified amorphously. The DSC thermograms are attached.

No other thermal effect from crystallisation or melting was registered upon further heating.

Conclusions:

No melting point was found between -150 and +50°C under the conditions of the study. A glass transition was observed at -143°C. The result is considered to be reliable.

Reference 2

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

2013-11-13 to 2013-11-14

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

The study was conducted in accordance with OECD 102 but not in compliance with relevant quality management system.

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: OECD 113 (1981) Screening test for thermal stability and stability in air

Version / remarks:

1981

Deviations:

no

GLP compliance:

no

Type of method:

thermal analysis

Remarks:

Differential Scanning Calorimeter

Key result

Melting / freezing pt.:

< -100 °C

Atm. press.:

1 013 hPa

Remarks on result:

other: Test item has no melting point above -100°C

Thermal stability (DSC measurement):

DSC measurement in a closed glass crucible showed an inconclusive base line. The DSC thermogram attached (figure 1).

Melting point/melting range (DSC measurement):

Two DSC measurements in aluminium crucibles with a hole showed no thermal effects in the temperature range of -100°C to room temperature. Therefore, the test item has no melting point above -100°C. The DSC thermograms attached (figure 2).

Conclusions:

The melting point of the substance was determined not to be above -100°C at 1013 hPa using a relevant test method. The result is considered to be reliable.

Description of key information

Melting point: <-1000°C at 1013 hPa (OECD 102)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-100 °C

Additional information

Two measured melting/freezing point studies are available for the registered substance. In Mekelburger 2012, a glass transition temperature of -143°C at 1013 hPa was determined for the substance in accordance with OECD Test Guideline 102 (DSC - Differential Scanning Calorimetry) and in compliance with a known quality system (ISO 17025). Similarly, in Ahrens 2013, the result of thermal stability testing using DSC, indicates the test item has no melting point above -100°C (i.e. <-100°C) at 1013 hPa. The results were considered to be reliable and are used as weight of evidence.

In a secondary source to which reliability could not be assigned, a melting point of <0°C was reported for the substance.