1-Butanone, 3-(dodecylthio)-1-[(1R,2S)-2,6,6-trimethyl-3-cyclohexen-1-yl]-, rel-

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 01 to 15 February 2006

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

OECD Guideline Study. Purity and isomers composition specified. Restrictions for inaccuracy due to extrapolation.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

Directive 92/69/EEC

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

UK GLP Compliance Programme (inspected on August 30, 2005 / signed on November 21, 2005)

Type of method:

effusion method: vapour pressure balance

Specific details on test material used for the study:

- Storage condition of test material: approximately 4°C in the dark under nitrogen

Temp.:

25 °C

Vapour pressure:

< 0.01 Pa

Remarks on result:

other: Extrapolated Vapour Pressure was 0.0000075 Pa at 25 °C

Transition / decomposition:

no

Mean extrapolated vapour pressure from each run = 0.0075 +/- 0.0004 mPa.

Determination coefficients (R2) for the 6 runs ranged between 0.9944 and 0.9989.

Regression equations and graphs are provided in the experimental reports.

Conclusions:

Very low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 0.01 Pa).

Executive summary:

The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline, vapour pressure balance method.

Six runs were conducted between 120 and 130°C. Vapor pressure at 25 °C was calculated by extrapolation from the mean.

The vapour pressure of the test item has been determined to be 0.0000075 Pa at 25°C.

Description of key information

Very low volatility (experimental, extrapolated).

Key value for chemical safety assessment

Vapour pressure:

0 Pa

at the temperature of:

25 °C

Additional information

A reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Despite restrictions for inaccuracy, due to distant extrapolation, it is considered as a key study. The result is retained as key data.