Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Two reliable key studies are available to assess the toxicity of the registered substance to earthworm. The first study (Harlan, 2011) assess the acute toxicity effects using the filter paper contact test according to OECD Guideline 207 and the second study (Fraunhofer, 2015) assess the chronic toxicity effects according to OECD Guideline 222.

In the first study (Harlan, 2011), no mortality on the earthworm, Eisenia fetida, was observed at the end of the 48h-test for all test concentrations used. Therefore, the 48h-EC50 was greater than the maximum tested concentration, 4.0 mg/cm².

In the second study (Fraunhofer, 2015), no increased mortality and no significant influence on weight change were found up to the maximum tested concentration, 1000 mg/kg dry soil. However, reproduction was significantly affected starting at 125 mg/kg dry soil. The NOEC for reproduction was found to be 62.5 mg/kg dry soil and the EC10 was found to be 116 mg/kg dry soil (95 % CL: 45 – 185 mg/kg dry soil). As NOECs are increasingly contested in ecotoxicology because they are not statistically interpolated values, the EC10 value at 116 mg/kg dry soil is prefered to assess the chronic effects.

In conclusion, the test substance has not acute effects on earthworm but was found to cause chronic effects, based on reproduction, under the chosen test conditions. The relevant chronic value is defined as the EC10 at 116 mg test substance/kg dry soil (95 % CL: 45 – 185 mg/kg dry soil).

Additional information