Registration Dossier
Registration Dossier
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EC number: 273-761-1 | CAS number: 69012-64-2 Amorphous silicon dioxide particles from the volatilization and vaporization of furnace feed materials in the manufacture of ferrosilicon and silicon.
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
A 10-day acute (mortality) Corophium volutator test resulted in LC50 > 50 000 mg/kg. The test showed some toxic effects in all tested concentrations and increased mortality in the exposed groups. Application of this study for PNEC sediment derivation is complicated, since long-term (non-acute) sediment tests (endpoint other than mortality) are normally used for PNECsediment derivation.
Key value for chemical safety assessment
- EC50 or LC50 for freshwater sediment:
- 50 000 mg/kg sediment dw
- EC10, LC10 or NOEC for freshwater sediment:
- 49 mg/kg sediment dw
Additional information
A 10 -day Corophium volutator test resulted in LC50 > 50 000 mg/kg. The test showed some toxic effects in all tested concentrations and increased mortality in the exposed groups. The determination of the concentration-response relationship of silica fume in the acute sediment test results lead to the identification of the median lethal concentration of LC50 > 50 000 mg/kg (dw). The test may be comparable to a limit test, since a true concentration –response relationship could not be determined. However, effects were seen in the lowest observed concentration.
For silica fume, not actually the Si, but the impurities present in the substances need consideration if exposure to sediment takes place. The amount and quality of impurities vary between raw materials, processes and factories. In estimation of hazard and risks involved in these metals or other impurities, further testing or the read across method may be utilized case by case. Already existing hazard data and PNECsediment values for these metals and other elements can be used.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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