Registration Dossier

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
before 1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Handbook data

Data source

Reference
Reference Type:
publication
Title:
Toxicometric Parameters of industrial toxic chemicals under single exposure
Author:
Izmerov, N.F., Sanotsky, I.V., Sidorov, K.K.
Year:
1982
Bibliographic source:
United Nations Environment Program et al. , Centre of International Projects, Moscow, 1982

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
not specified
Test type:
other: not reported
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
no data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
no data

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
other: no data
Details on inhalation exposure:
no data
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
2 h
Concentrations:
not mentioned
No. of animals per sex per dose:
no data
Control animals:
no
Details on study design:
no data
Statistics:
no data

Results and discussion

Preliminary study:
no data
Effect levels
Sex:
male/female
Dose descriptor:
LC50
Effect level:
390 mg/m³ air
Exp. duration:
2 h
Remarks on result:
other: The LC50 for mice is reported to be 360 */- 44 mg/m3.
Mortality:
not reported
Clinical signs:
other: not reported
Body weight:
not reported
Gross pathology:
not reported
Other findings:
not reported

Applicant's summary and conclusion

Interpretation of results:
highly toxic
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Substance is very toxic if inhaled.