Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 229-347-8 | CAS number: 6484-52-2
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Adequacy of study:
- supporting study
- Reliability:
- other: no data
Data source
Reference
- Reference Type:
- publication
- Title:
- Mortality of nitrate fertilizer workers
- Author:
- Al-Dabbagh, S., Forman, D., Bryson, D., Stratton, I., and Doll, R.
- Year:
- 1 986
- Bibliographic source:
- British Journal of Industrial Medicine. 43:507-515.
Materials and methods
- Type of study / information:
- no data
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- nitrates (fertilizer)
- IUPAC Name:
- nitrates (fertilizer)
- Details on test material:
- no data
Constituent 1
Method
- Details on study design:
- no data
- Exposure assessment:
- not specified
Results and discussion
- Results:
- No significant excess was observed for all causes of mortality or for mortality from any of five broad categories of cause or from four specific types of cancer. This was true for the entire cohort as well as for a subgroup that had been heavily exposed to nitrates.
Any other information on results incl. tables
A total of 1327 male workers engaged in the production of nitrate based fertilizers between 1946 and 1981 were tracked until 1981. In addition, a subgroup consisting of workers heavily exposed to nitrate, defined as working in an environment likely to contain more than 10 mg NO3/m3for a year or longer, was separately analyzed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
