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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

Currently viewing:

Administrative data

Endpoint:
carcinogenicity, other
Remarks:
not specified
Type of information:
not specified
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Mortality of nitrate fertilizer workers
Author:
Al-Dabbagh, S., Forman, D., Bryson, D., Stratton, I. and Doll, R.
Year:
1986
Bibliographic source:
British Journal of Industrial Medicine. 43:507-515.
Reference Type:
publication
Title:
Effect of nitrate and nitrite in drinking water in rats.
Author:
Chow, C.K., Chen, C.J. and Gairola, C.
Year:
1980
Bibliographic source:
Toxicology Letters. 6:199-206.
Reference Type:
publication
Title:
Nitrates, nitrites and gastric cancer in Great Britain.
Author:
Forman, D., Al-Dabbagh, S. and Doll, R.
Year:
1985
Bibliographic source:
Nature. 313(6004):620-625.
Reference Type:
publication
Title:
Nitrates in drinking water and cancer.
Author:
Leclerc, H., Vincent, P. and Vandevenne, P.
Year:
1991
Bibliographic source:
Bull. Acad. Natl. Med. 175(4):651-666.
Reference Type:
publication
Title:
Nitrosamines as environmental carcinogens.
Author:
Lijinsky, W. and Epstein, S.S.
Year:
1970
Bibliographic source:
Nature 225(227):21-23. nitroso compounds. Adv. Cancer Res. 10:163-264.
Reference Type:
publication
Title:
Environmental cancer risks – real and unreal.
Author:
Lijinsky, W
Year:
1989
Bibliographic source:
Environmental Research 50:207-209.
Reference Type:
publication
Title:
Carcinogenic nitroso compounds.
Author:
Magee, P.N. and Barnes, J.M.
Year:
1967
Bibliographic source:
Adv. Cancer Res. 10:163-264.

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
nitrates
IUPAC Name:
nitrates

Test animals

Species:
other: No data
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: no data
Type of inhalation exposure (if applicable):
not specified
Vehicle:
not specified
Duration of treatment / exposure:
no data
Frequency of treatment:
no data
Post exposure period:
no data
No. of animals per sex per dose:
no data

Results and discussion

Any other information on results incl. tables

no data

Applicant's summary and conclusion