Registration Dossier
Registration Dossier
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EC number: 808-279-8 | CAS number: 88938-51-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The NOEC of Disperse Blue ANT is 32 mg/L.The test item is not toxic up to the concentration of 32 mg/L to activated sludge of a municipal sewage treatment plant. The EC10 is 89.9 mg/L, the EC20 is 129 mg/L, the EC50 is 340 mg/L. The EC80 of the test item is > 1000 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 340 mg/L
- EC10 or NOEC for microorganisms:
- 32 mg/L
Additional information
A Respiration Inhibition Test with activated sludge according to OECD Guideline No. 209 was carried out with the test item Disperse Blue ANT. The test system was activated sludge of the municipal treatment plant of 31137 Hildesheim, Germany. The test was carried out under static conditions with the test item concentrations 10 - 32 - 100 - 320 - 1000 - 1000 pH mg/L. The respiration rates of the control, reference and test item replicates were measured after a contact time of three hours, and the inhibitory effects of the test and reference item were determined in comparison to the control respiration rates. The mean inhibition of respiration for the test item replicates ranged from -13 % to 63 %.
In order to check the activity of the test system and the test conditions a reference test was carried out with copper (II) sulphate pentahydrate as reference item and the reference toxicity was determined. The EC50-value for the reference item was 86.5 mg/L.
NOEC and EC-Values with Confidence Interval of Disperse Blue ANTafter 3 h exposure time, Inhibition of Total Respiration
|
EC-values |
Confidence interval |
NOEC* |
32 |
– |
EC10 |
89.9 |
70.8 – 111 |
EC20 |
129 |
106 – 153 |
EC50 |
340 |
270 – 431 |
EC80 |
> 1000 |
– |
The NOEC of Disperse Blue ANT is 32 mg/L.The test item is not toxic up to the concentration of 32 mg/L to activated sludge of a municipal sewage treatment plant. The EC10 is 89.9 mg/L, the EC20 is 129 mg/L, the EC50 is 340 mg/L. The EC80 of the test item is > 1000 mg/L. |
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