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EC number: 205-571-1
CAS number: 142-91-6
Table 1: Maximum number of revertants
Maximum number of revertants (dose level [µg/mL])
Table 2: Maximum relative number of revertants
Maximum relative number of revertants (dose level [µg/mL])
The results for TA 1537 without S9 -mix were not valid. Although the
targets of reverse mutations are different in TA 1537 and TA 98, the
possible mutational event in both strains is frameshift. TA 98 is
additionally more sensitive to mutations because it carries the R-factor
(pKM101) plasmid. The fact that there is no increase in revertants in TA
98 without S9 -mix, gives evidence that there would be no increase of
revertants in TA 1537 as well. Therefore it can be concluded that the
test substance showed no increase in the number of revertants at any
concentration in any tester strain. The test substance is non-mutagenic.
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