Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-468-3 | CAS number: 95-96-5
Endpoint summary
Administrative data
Description of key information
EC50 (fish, 96 h) = 130 - 320 mg/L
EC50 (daphnids, 48 h) = 130 - 750 mg/L
NOEC (algae, 72 h) > 533 mg/L
NOEC (microorganisms, 3 h) ≥ 88.2 mg/L
Additional information
Since Dilactide undergoes immediate hydrolysis in contact with water, forming lactic acid, this is the moiety of interest by read-across.
The aquatic toxicity of L-lactic acid is primarily related to its effects on pH of the test solution if not buffered. Both the fish and daphnid studies were not buffered, the algae study was buffered. Hence, effects on fish and daphnids were attributed to a pH shift. Whereas effects in the algae study can be assigned to the test substance and are not confounded with pH effects due to the acidity of lactic acid.
No effects on microbial growth were observed in an activated sludge respiration inhibition test.
Both L- and D-lactic acid are ubiquitous and essential molecules in all biological systems, and organisms are continuously exposed to significant internal and external background concentrations of L- as well as D-lactic acid. Therefore, the information on the aquatic toxicity of L-lactic acid is fully valid for D-lactic acid, and in consequence for dilactide.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
