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EC number: 202-468-3 | CAS number: 95-96-5
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0.28 Pa
- Remarks on result:
- other: modified Grain method
- Conclusions:
- The vapour pressure of D-lactide is 0.28 Pa at 25 °C, obtained by QSAR calculation.
- Executive summary:
The vapour pressure of D-lactide was estimated by QSAR calculation (MPBPWin v1.43, EpiSuite). Experimental values for melting point and boiling point were taken into account. The resulting vapour pressure of D-lactide is 0.28 Pa at 25 °C.
This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Endpoint:
- vapour pressure
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0.311 Pa
- Remarks on result:
- other: modified Grain method
- Conclusions:
- The vapour pressure of L-lactide is 0.311 Pa at 25 °C, obtained by QSAR calculation.
- Executive summary:
The vapour pressure of L-lactide was estimated by QSAR calculation (MPBPWin v1.43, EpiSuite). Experimental values for melting point and boiling point were taken into account. The resulting vapour pressure of L-lactide is 0.311 Pa at 25 °C.
This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Referenceopen allclose all
Description of key information
By read-across from the enantiomers D-lactide and L-lactide, the vapour pressure of dilactide is estimated to be 0.311 Pa in a worst-case approach.
Key value for chemical safety assessment
- Vapour pressure:
- 0.311 Pa
- at the temperature of:
- 25 °C
Additional information
Reliable QSAR calculations for the vapour pressure of D-lactide and L-lactide are available. The slightly differ since the calculations take into account measured melting points as correction factor. Slightly deviating melting points results from unavoidable measurement inaccuracies. From the two vapour pressure estimates (0.311 Pa for L-lactide, 0.28 for D-lactide) the higher one is adopted for dilactide in a worst-case approach.
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