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EC number: 701-257-8 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No OECD guideline study or GLP defined, no data on purity of test sample, no dose defined, no sex defined.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
Materials and methods
- Principles of method if other than guideline:
- Method: other: human n=7, saturated patch, right forearm, 24 h exposure, observation period: 7 days
- GLP compliance:
- not specified
Test material
- Reference substance name:
- C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
- EC Number:
- 701-257-8
- IUPAC Name:
- C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- human
- Strain:
- not specified
Test system
- Type of coverage:
- other: ball of absorbent cotton and adhesive bandage
- Preparation of test site:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Controls:
- other: no control test persons described
- Duration of treatment / exposure:
- 24 h
- Observation period:
- 7 d
- Number of animals:
- 7 test persons
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- other: 7 volunteers
- Time point:
- other: 8 h
- Score:
- ca. 0
- Max. score:
- 8
- Reversibility:
- other: no effects observed
- Remarks on result:
- other: In a study in 7 humans the test substance (no dose defined) was applied to the right forearm and fixed with a ball of absorbent cotton and adhesive bandage for 24 hours. The observation:7d. No skin irritating or corrosive effects could be observed.
Any other information on results incl. tables
No skin irritating or corrosive effects observed.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Executive summary:
In a study in 7 humans (no sex defined) the test substance (no dose defined) was applied to the right forearm and fixed with a ball of absorbent cotton and adhesive bandage for 24 hours. The observation period was 7 days. No skin irritating or corrosive effects could be observed.
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