Registration Dossier
Registration Dossier
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EC number: 701-257-8 | CAS number: -
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No OECD guideline or GLP defined; no data on purity of test sample
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
Materials and methods
- Principles of method if other than guideline:
- other: acute i.p. toxicity study in male rats
- GLP compliance:
- not specified
- Limit test:
- yes
Test material
- Reference substance name:
- C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
- EC Number:
- 701-257-8
- IUPAC Name:
- C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 5.0 ml/kg
- No. of animals per sex per dose:
- 10 male rats/dose
- Control animals:
- not specified
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 5 275 mg/kg bw
Any other information on results incl. tables
| Dose (ml/kg bw) | Timepoint of death | Toxicological result (Nr.of mortalities/Animals with symptoms/No.of animals) |
| 5.0 | - | 0/0/10 |
Applicant's summary and conclusion
- Executive summary:
The acute intraperitoneal toxicity of Mesamoll was tested in male Wistar rats. The dose tested was 5.0 ml/kg bw.
No mortalities and no signs of intoxication could be observed.
Regarding the density of Mesamoll (1.055 g/cm³ at 20 °C) the LD 50 was higher than 5275 mg/kg bw.
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