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Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From Aug. 17, 2010 to Sept. 29,2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to standard guidelines in compliance with GLP.
Justification for data waiving:
other:
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. QA statement)
Type of method:
method according to Siwoloboff

Test material

Constituent 1
Chemical structure
Reference substance name:
12-hydroxystearic acid
EC Number:
203-366-1
EC Name:
12-hydroxystearic acid
Cas Number:
106-14-9
Molecular formula:
C18H36O3
IUPAC Name:
12-hydroxyoctadecanoic acid
Details on test material:
- Name of test material (as cited in study report): 12-hydroxystearic acid
- Physical state: Solid / white to yellowish
- Certificate of analysis date: 09 April 2010
- Expiration date of the lot/batch: 09 April 2011
- Storage condition of test material: In original container, at room temperature (15 - 25°C), in the dark

Results and discussion

Boiling point
Boiling pt.:
265 °C
Atm. press.:
101.3 kPa
Remarks on result:
other: none

Any other information on results incl. tables

Table 1. Results for the Determination of the Boiling Point of 12-hydroxystearic acid

Replicate no. Pressure [kPa] Temperature [°C]  Temperature [K]  corrected*
Temperature [°C]   Temperature [k]
1 99.63 263.7 536.9 264.4 537.6
2 99.63 264.2 537.4 264.9 538.1
3 99.63 263.9 537.1 264.6 537.8
4 99.62 265.2 538.4 265.9 539.1
5 99.62 265.9 539.1 266.6 539.8
6 99.62 264.3 537.5 265.0 538.2
  mean value (n=6):  264.5 537.7 265.2 538.4

*corrected by correlation factor 0.42 K/kPa (y = 0.0008 * x - 0.009) and barometric pressure

Applicant's summary and conclusion

Conclusions:
The boiling point of the test substance was found to be 265°C at 101.3 kPa.
Executive summary:

The boiling point of 12-hydroxystearic acid was determined by the capillary method (Siwoloboff) method using a electronically-controlled heating system according to OECD Guideline 103, EU Method A.2 and EPA OPPTS 830.7220.

In the preliminary test, a sample of the test substance in a capillary glass tube was heated from about 26°C up to about 400 ºC with a rate of approximately 10 ºC/min to estimate phase transition (formation of steam bubbles) temperature. For the actual determination of the boiling point, the temperature rise adjusted to a maximum of 1°C/min at about 15°C before and after the predetermined phase transition temperature.

 

The boiling point of test substance was found to be 265°C at 101.3 kPa.