12-hydroxystearic acid

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From Aug. 17, 2010 to Sept. 29,2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study was conducted according to standard guidelines in compliance with GLP.

Justification for data waiving:

other:

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Test material

Test material information

Constituent 1

Reference substance name:

12-hydroxystearic acid

EC Number:

203-366-1

EC Name:

12-hydroxystearic acid

Cas Number:

106-14-9

Molecular formula:

C18H36O3

IUPAC Name:

12-hydroxyoctadecanoic acid

Details on test material:

- Name of test material (as cited in study report): 12-hydroxystearic acid
- Physical state: Solid / white to yellowish
- Certificate of analysis date: 09 April 2010
- Expiration date of the lot/batch: 09 April 2011
- Storage condition of test material: In original container, at room temperature (15 - 25°C), in the dark

Results and discussion

Boiling point

Boiling pt.:

265 °C

Atm. press.:

101.3 kPa

Remarks on result:

other: none

Any other information on results incl. tables

Table 1. Results for the Determination of the Boiling Point of 12-hydroxystearic acid

Replicate no.	Pressure [kPa]	Temperature [°C]	Temperature [K]	corrected*
				Temperature [°C]	Temperature [k]
1	99.63	263.7	536.9	264.4	537.6
2	99.63	264.2	537.4	264.9	538.1
3	99.63	263.9	537.1	264.6	537.8
4	99.62	265.2	538.4	265.9	539.1
5	99.62	265.9	539.1	266.6	539.8
6	99.62	264.3	537.5	265.0	538.2
	mean value (n=6):	264.5	537.7	265.2	538.4

*corrected by correlation factor 0.42 K/kPa (y = 0.0008 * x - 0.009) and barometric pressure

Applicant's summary and conclusion

Conclusions:

The boiling point of the test substance was found to be 265°C at 101.3 kPa.

Executive summary:

The boiling point of 12-hydroxystearic acid was determined by the capillary method (Siwoloboff) method using a electronically-controlled heating system according to OECD Guideline 103, EU Method A.2 and EPA OPPTS 830.7220.

In the preliminary test, a sample of the test substance in a capillary glass tube was heated from about 26°C up to about 400 ºC with a rate of approximately 10 ºC/min to estimate phase transition (formation of steam bubbles) temperature. For the actual determination of the boiling point, the temperature rise adjusted to a maximum of 1°C/min at about 15°C before and after the predetermined phase transition temperature.

 

The boiling point of test substance was found to be 265°C at 101.3 kPa.