Registration Dossier

Administrative data

Description of key information

Skin irritation/corrosion: no irritating
Eye irritation: category 1: irreversible effects on the eye

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Skin irritation/corrosion:

A test of the registered substance was performed on skin irritation/corrosion in vivo according to OECD Guideline 404: acute dermal irritation/corrosion in a certified GLP labs. The study can be ranked as klimisch code 1: reliability without restrictions. The results showed that no toxic effect was found. and other two in vitro studies also support this result. So the irritative effect of tartaric acid can be concluded as no irritating.

Eye irritation:

An in vitro test of the registered substance was performed on eye irritation complying with OECD Guideline 437: Bovine Corneal Opacity and Permeability Test Method for identifying ocular corrosives and severe irritants. This study is regarded as key study as it can be ranked as klimisch code 1: reliability without restrictions. And the test result showed that tartaric acid is highly irritating.


Effects on eye irritation: highly irritating

Justification for classification or non-classification

Skin irritation/corrosion:

According to Official Journal of the European Union 1272/2008 (CLP) dated December 16th 2008, tartaric acid is non-classified in this part.

Eye irritation:

According to OECD Guideline 437: Bovine Corneal Opacity and Permeability Test Method for identifying ocular corrosives and severe irritants and Official Journal of the European Union 1272/2008 (CLP) dated December 16th 2008, tartaric acid can be classified as: category 1: irreversible effects on the eye.