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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

The following information is available for this endpoint:
MacGregor, J.A. and Nixon, W.B. (1997) Hexabromocyclododecane (HBCD): Determination of n-octanol/water partition coefficient, Wildlife International Ltd., 8598 Commerce Drive, Easton, Maryland 21601, 439C-104, Chemical Manufacturers Association's Brominated Flame Retardant Industry Panel, 1300 Wilson Boulevard, Arlington, Virginia 22209, 23/05/1997.
Hayward, S.J., Lei, Y.D & Wania, F. (2006) Comparative Evaluation of Three High-Performance Liquid Chromatography-Based Kow Estimation Methods for Highly Hydrophobic Organic Compounds: Polybroiminated Diphenyl Ethers and Hexabromocyclododecane, Environmental Toxicology and Chemistry (2006), Vol. 25, No. 8, PP. 2018-2027.
MacGregor & Nixon (1997) was selected as the key study based upon the reliability score of 2 assigned according to the criteria of Klimisch et al. (1997) and the thorough reporting of methodologies and results.
Hayward et al, 2006, was also scored 2 for reliability according to the same criteria, however provided less complete reporting of methodologies and results. Hayward et al, 2006, also used none-standard test methodologies which further reduced the reliability of the result.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
25 °C

Additional information

The measured log Kow of the commercial product was 5.625 at 25 ºC ± 0.005 ºC (MacGregor and Nixon (1997)). A literature report of the individual diastereomers (Hayward et al. (2006)) is consistent with this result.

α-isomer: 5.07 ± 0.09

ß-isomer: 5.12 ± 0.09

γ-isomer: 5.47 ± 0.1