Registration Dossier
Registration Dossier
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EC number: 265-163-4 | CAS number: 64742-60-5 A complex combination of hydrocarbons obtained by treating a petroleum microcrystalline wax with hydrogen in the presence of a catalyst. It consists predominantly of long, branched chain hydrocarbons having carbon numbers predominantly in the range of C25 through C50.
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Read across justification
Several criteria justify the use of the read across approach to fill data gaps for paraffin and hydrocarbon waxes using other lubricant base oil analogs. Primarily the basis for the read-across is the similar physical chemical properties shared by the paraffin and hydrocarbon waxes and other lubricant base oils.
In a read-across key semi-static 21-day long-term Daphnia magna toxicity test (OECD 211; KS = 2), 10 animals/loading were exposed to the Water Accommodated Fraction (WAF) of other lubricant base oil LVIN 38 (CAS #64742-53-6) at nominal concentrations of 1, 10, 100 and 1000 mg/L. The NOEL was 10 mg/L based on reproduction. The loss of all daphnids in the 100 mg/L WAF was attributed to a non-treatment related effect, the cause of which was unknown. Further testing would be required to clarify the consequences of exposure to a 100 mg/L WAF of the base oil (Shell, 1995).
This study is scientifically sound and satisfies the guideline requirements for long-term toxicity to aquatic invertebrates.
Supporting data estimated from the PETROTOX computer model show no acute toxicity of paraffin and hydrocarbon wax to freshwater invertebrates at or below its maximum attainable water solubility (Redman et al., 2010b). These data support the applied read across.
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