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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: scientifically accepted study
Qualifier:
no guideline followed
Principles of method if other than guideline:
The particle size distribution was determined using a Mastersizer laser light scattering analyzer (model MAM 5005, Malvern Instruments Ltd., Worcestershire, UK). A small quantity of powder was dispersed in 99.5% ethanol and the particle distribution monitored during five successive readings. The particle size was expressed as the mean volumetric size D4,3 (De Brouckere mean diameter), which is the mean diameter of a sphere with the same volume, and is generally used to characterize a particle.
GLP compliance:
not specified
Type of method:
Laser scattering/diffraction
Type of particle tested:
other: powder
Type of distribution:
volumetric distribution
Key result
Mean:
5.8 µm
St. dev.:
0.1
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
No.:
#1
Remarks on result:
other: no data
Conclusions:
volumetric mean diameter D4,3 mean=5.8 μm

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