Protein hydrolyzates, animal

Endpoint summary

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records

Reference

Endpoint:

acute toxicity: oral

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test type:

fixed dose procedure

Limit test:

yes

Specific details on test material used for the study:

Pig trachea hydrolyzate proteins

Species:

rat

Strain:

Wistar

Sex:

female

Route of administration:

oral: gavage

Vehicle:

water

Doses:

2.000 mg/Kg bw

No. of animals per sex per dose:

6 females

Control animals:

no

Key result

Sex:

female

Dose descriptor:

LD50

Effect level:

> 2 000 mg/kg bw

Based on:

test mat.

Interpretation of results:

practically nontoxic

Remarks:

Migrated information Criteria used for interpretation of results: EU

Conclusions:

According to the results obtained in the study and according to the Globally Harmonized System
(GHS), the test is classified as Category 5/No classified.
Under the system currently used in the European Union (Directive 2004/73/EC,Annex 2B) and the criteria published in the Official Journal of the European Communities 6 August 2001 (Directive 2001/59/EC, Annex VI), we conclude that the product MOSCA
TRAP is considered "NOT CLASSIFIED", so there is no need to assign risk notation.

Endpoint conclusion

Endpoint conclusion:

no adverse effect observed

Dose descriptor:

LD50

Value:

2 000 mg/kg bw