Registration Dossier
Registration Dossier
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EC number: 220-449-8 | CAS number: 2768-02-7
Carcinogenicity
Administrative data
Description of key information
A study for the endpoint ‘carcinogenicity’ is not required according to REACH Annex X, 8.9.1. It was concluded in the genetic toxicity section that the substance does cause chromosomal aberrations in vitro in the presence of metabolic activation, however this potential for genetic toxicity was not confirmed in in vivo studies, so it was concluded that trimethoxy(vinyl)silane (CAS 2768-02-7; EC No. 220-449-8) is not mutagenic. Following annex X, 8.9.1 no studies for carcinogenic effects are required for substances that are not mutagenic.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
There is no evidence to suggest that the substance should be classified for carcinogenicity.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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