Registration Dossier
Registration Dossier
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EC number: 220-449-8 | CAS number: 2768-02-7
Endpoint summary
Administrative data
Description of key information
Three producers of trimethoxy(vinyl)silane (CAS 2768-02-7; EC No. 220-449-8) have provided statements which confirm that there have been no cases of skin sensitisation amongst workers during more than 40 years of manufacture (Wacker, 2017; Momentive, 2013 and 2017; Evonik Degussa, 2017).
These data included internal information from: relevant plants, number of employees, exposure description; medical surveillance, regular health checks (especially concerning skin status) already performed on employees of the relevant plants, information from the Network of Departments of Dermatology for the surveillance and scientific evaluation of contact allergies, information from Employer's liability insurance association (BG Bau), information from customer and a comprehensive literature search there have been no cases of skin sensitisation during more than 20 years of production, handling and use of trimethoxy(vinyl)silane.
There is therefore no evidence that this substance causes skin sensitisation under relevant exposures in workers.
Additional information
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