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EC number: 220-449-8
CAS number: 2768-02-7
Reliable short-term toxicity tests
results are available for freshwater fish (Oncorhynchus mykiss),
invertebrates (Daphnia magna) and algae (Pseudokirchneriella
subcapitata) for the registered substance, trimethoxy(vinyl)silane
(CAS 2768-02-7). The relevant short-term values are:
Fish: LC50 (96
h): 137 mg/L expressed in terms of concentration of the hydrolysis
Daphnia: EC50 (48
h): 121 mg/L expressed in terms of concentration of the hydrolysis
Algae: EC50 (72
h): >64 mg/L; NOEC: =64 mg/L expressed
in terms of concentration of the hydrolysis product, vinylsilanetriol.
Long-term data are available with
invertebrates (Daphnia magna):
21-day NOEC: 20 mg/L expressed in
terms of concentration of the hydrolysis product, vinylsilanetriol.
The very rapid hydrolysis of
trimethoxy(vinyl)silane (CAS 2768-02-7) (half-life 0.1 h at pH 7 and
20-25°C) means it is likely that the test organisms in each test were
exposed primarily to the hydrolysis products, vinylsilanetriol and
There are no reliable
microorganism toxicity data available for trimethoxy(vinyl)silane (CAS
2768-02-7), therefore good quality data for the structurally-related
substance, trichloro(vinyl)silane (CAS 75-94-5), have been read across.
Both substances share the same silanol hydrolysis product,
vinylsilanetriol. The other hydrolysis products are methanol and
hydrogen chloride / chloride salts respectively.
Refer to IUCLID Section 6 endpoint
summary (CSR Section 7.0) for further discussion of the approach to
chemical safety assessment and justification for read-across.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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