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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

96-hour LC50: 191 mg/L, for effects of the test substance on mortality of Oncorhynchus mykiss. It is likely that the test organism were primarily exposed to the hydrolysis product of the test substance. The LC50 is equivalent to 137 mg/L when expressed in terms of the silanol hydrolysis product vinylsilanetriol.

Key value for chemical safety assessment

LC50 for freshwater fish:
137 mg/L

Additional information

A 96-hour LC50 value of 191 mg/L (nominal concentration) has been determined for the effects of the test substance on mortality of Oncorhynchus mykiss (Dow Corning 1979). It is likely that the test organisms were primarily exposed to the hydrolysis product of the test substance. The results may be expressed in terms of the silanol hydrolysis product, by adjusting for the respective molecular weights: MW hydrolysis product/MW parent * E(L)C50 or NOEC value, thus 106.15/148.24 * LC50 of 191 mg/L = 137 mg/L as vinylsilantriol.

The results of this test were selected in preference to those of two available studies with higher reliability scores, because a definitive (although comparable) LC50 value was determined. Other available test results were less reliable or gave greater-than limit results. The following results are from studies included as supporting data:

96-hour LC50 >1000 mg/L for effects of the test substance on mortality of Lepomis macrochirus (Dow Corning, 1979).

96-hour LC50 >100 mg/L for effects of the test substance on mortality of Danio rerio ( Scholz, 1995).

96-hour LC50 >100 mg/L for effects of the test substance on mortality of Oncorhynchus mykiss (Bement, 2001).

96-hour LC50 >92.2 mg/L for effects of the test substance on mortality of Oryzias latipes (MOE, 2006).

A further study, for which the reliability could not be ascertained, is also included in the dataset: LC50 >2000 mg/L for effects of the test substance on mortality of Pimephales promelas (Chandra, 1997).