2,2,4-trimethyl-4-phenyl-butane-nitrile

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1996

Report date:

1996

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: 92/69/EEC, C3

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

2,2,4-trimethyl-4-phenyl-butane-nitrile

EC Number:

422-580-8

EC Name:

2,2,4-trimethyl-4-phenyl-butane-nitrile

Cas Number:

75490-39-0

Molecular formula:

C13 H17 N

IUPAC Name:

2,2-dimethyl-4-phenylpentanenitrile

Test solutions

Details on test solutions:

Identity and concentration of auxiliary solvent for dispersal: The test substance was dispersed in sterile nutrient medium
by stirring for two hours. This was further diluted with
sterile nutrient medium to give a series of solutions with
concentrations appropriate to the intended exposure levels.

Test organisms

Test organisms (species):

Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Limit test:

no

Total exposure duration:

72 h

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

11 mg/L

Basis for effect:

biomass

Effect concentrations 2

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

12 mg/L

Basis for effect:

growth rate

Effect concentrations 3

Duration:

72 h

Dose descriptor:

NOEC

Effect conc.:

4.5 mg/L

Basis for effect:

biomass

Details on results:

%Concentration loss over test: 29 ... 0