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Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report date:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EEC, C7
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
EC Number:
422-580-8
EC Name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
Cas Number:
75490-39-0
Molecular formula:
C13 H17 N
IUPAC Name:
2,2,4-trimethyl-4-phenyl-butane-nitrile

Results and discussion

Preliminary study:
Comments: Under the preliminary test conditions, Khusinil was found to undergo marginal hydrolysis at pH 7 (12%), moderate hydrolysis at pH 9 (19%), but no significant hydrolysis at pH 4, after 5 days at 50 deg C. Under test 1 conditions, Khusinil was found to undergo a pseudo first order reaction, therefore, test 3 was carried out at 60 and 70 deg C at pH 7 and pH 9.  The results indicate that the half-life times at 25 deg C are greater than one year at pH 7 and between one day and one year at pH 9.
Transformation products:
not measured

Applicant's summary and conclusion

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