Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report date:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EEC, C1
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
EC Number:
422-580-8
EC Name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
Cas Number:
75490-39-0
Molecular formula:
C13 H17 N
IUPAC Name:
2,2,4-trimethyl-4-phenyl-butane-nitrile

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: The test substance was dispersed directly in test water, by
stirring for two hours, to give a series of stock solutions.

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
static

Test conditions

Hardness:
159 mg CaCO3/L

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 8.4 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
< 0.86 mg/L
Details on results:
%Concentration loss over test: 0 ... 60

Applicant's summary and conclusion

Categories Display